Search on: PUBERTY, PRECOCIOUS 
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Descriptor English:   Puberty, Precocious 
Descriptor Spanish:   Pubertad Precoz 
Descriptor Portuguese:   Puberdade Precoce 
Tree Number:   C19.391.693
Definition English:   Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE. 
Indexing Annotation English:   human only
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications DI diagnosis
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RA radiography RI radionuclide imaging
RT radiotherapy RH rehabilitation
SU surgery TH therapy
US ultrasonography UR urine
VI virology  
Record Number:   12064 
Unique Identifier:   D011629 

Occurrence in VHL: 		 

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